Natural therapy: Dietary

Showing posts with label Dietary. Show all posts

Friday, June 21, 2013

Dietary supplement of bovine meat, oysters from brain disorders of fighting

by Sheela Philomena on May 25, 2013 at 12:23 News Diet & Nutrition phosphatidylserine - food supplement produced from beef, soya and oyster has been found to improve cognition and slow memory. Help of phosphatidylserine degenerative brain disorders combat, including Parkinson's disease and the Familial Dysautonomia (FD). Food Supplement from Beef, Oysters Fights Brain Disorders
It's the determination made by a team led by Professor Gil Ast and Dr. Ron Bochner of the Tel Aviv University Department of Human Molecular Genetics.

FD, a rare genetic disease that impact on the nervous system and seems almost exclusively among the Ashkenazi Jewish population, a genetic mutation prevents the brain from the manufacture of IKAP protein in good health - probably with a hand in cell migration and help connections between nerves - leading to early degeneration of neurons.

When the supplement was applied to cells taken from patients of the FD, the improved gene function and elevation of the IKAP protein level was observed, reports Prof. Ast.

These results have been replicated in a second experiment, to administer the supplement orally to populations of mice with FD.

The results are very encouraging, said Prof. Ast.

"We see such an effect on the brain - the most important body in relation to this disease - shows that the supplement can cross the blood - brain barrier even when administered by the oral route and accumulate in sufficient quantities in the brain," he said.

Already approved for use in addition to the FDA, phosphatidylserine contains an essential molecule for the transmission of signals between nerve cells in the brain. Prof. Ast and fellow researchers decided to check if the same chemical that is naturally synthesized in the body and known to increase the memory capacity, that could affect the genetic mutation that leads to FD.

Researchers have applied a supplement derived from oysters, supplied by the Israeli firm Enzymotec, FD patients cells. Noticing a strong effect on the gene, including a jump in the production of IKAP protein in good health, they then tested the same supplement on murine models of FD, designed with the same genetic mutation that causes the disease in humans.

The mice received the supplement orally, every two days for a period of three months. Then, researchers conducted genetic tests comprehensive to evaluate the results of the treatment.

"We found a significant increase of protein in all tissues of the body," revealed Prof. Ast, including an increase in liver and increased in the brain.

"While the dietary supplement manufactures not new nerve cells, it delays probably the death of those that already exist," he added.

The supplement is able to improve the conditions in the brain, even when administered orally, is an important finding, distinguished professor of Ast.

In addition, according to the researchers, that the positive effects of the supplement to extend beyond the production of IKAP. Not only impacted phosphatidylserine gene associated with FD, but it has also changed the level of a total of 2400 other genes - hundreds of which have been connected to Parkinson's disease in previous studies.

Researchers believe that the supplement can have a beneficial effect on a number of degenerative diseases of the brain, concluded Professor Ast, including significant potential for the development of new drugs that would help the tens of millions of people around the world suffering from these devastating diseases.

The results were published in the journal Human Molecular Genetics.

Source-ANI

var xmlHttpvar imgpath, imagefunction RefreshImage (ImageId) {image = document.getElementById (ImageId) //alert (ImageId); xmlHttp = GetXmlHttpObject (); if (xmlHttp == null) {alert ("your browser does not support AJAX!"); return;} var url="http://www.medindia.net/captcha/captcha.asp";url=url+"?x="+Math.random();imgpath=url;xmlHttp.onreadystatechange=stateChangedReg;xmlHttp.open("GET",url,true);xmlHttp.send(null);} function stateChangedReg() {if (xmlHttp.readyState == 4) {image.src = imgpath;}}function RequestCode() {xmlHttp = GetXmlHttpObject (); if (xmlHttp == null) {alert ("your browser does not support AJAX!"); return;} var url="http://www.medindia.net/captcha/reqimgvalue.asp";url=url+"?x="+Math.random();xmlHttp.onreadystatechange=stateChangedReq;xmlHttp.open("GET",url,true);xmlHttp.send(null);} function stateChangedReq() {if (xmlHttp.readyState == 4) {var seccode = xmlHttp.responseText; if (seccode == document.getElementById ('scode') .value) {//alert (seccode + "same value");}}}else {document.getElementById("SCODE").{{{Value = xmlHttp.responseText;}}}function GetXmlHttpObject() {var xmlHttpNew = null; try {/ / Firefox, Opera 8.0 +, Safari xmlHttpNew = new XMLHttpRequest();}}catch (e) {/ / Internet Explorer try {xmlHttpNew = new ActiveXObject ("Msxml2.XMLHTTP");} catch (e) {xmlHttpNew = new ActiveXObject ("Microsoft.XMLHTTP");}}{Return xmlHttpNew;}function GetXmlHttpObject() {var xmlHttp = null; try {/ / Firefox, Opera 8.0 +, Safari xmlHttp = new XMLHttpRequest();}}catch (e) {/ / Internet Explorer try {xmlHttp = new ActiveXObject ("Msxml2.XMLHTTP");} catch (e) {xmlHttp = new ActiveXObject ("Microsoft.XMLHTTP");}}{return xmlHttp;}

View the original article here

Sunday, June 16, 2013

Self-Reported Dietary Fibs Distort Survey Results

Assessments of diet in researches are usually based on self-report methods but the validity of these methods is dependent on the accuracy with which participants record their dietary intake. Under-reporting in self-reported dietary methods is a well-documented phenomenon among adults.

But why don't we tell the truth in surveys? Is it because we want to present a positive image of ourselves to friends, family and colleagues? It is a bias and it has a term - Social desirability bias.

The existence of systematic bias in dietary self-reports has been confirmed by many studies and research is on regarding methods of correcting for measurement error.

In an NIH funded Women's Health Initiative-Nutrition & Physical Activity Assessment Study (WHI-NPAAS), Yasmin Mossavar-Rahmani, associate professor of clinical epidemiology and population health at the Albert Einstein College of Medicine of Yeshiva University, New York, and her colleagues examined the extent to which psychosocial and diet behavior factors can affect self-report and how they can improve the assessment methodologies, viz. food frequency questionnaire (FFQ), four day food record (4DFR) and 24 hour dietary recall (24HR).

The researchers used doubly labeled water and urinary nitrogen as biomarkers of objective measures of total energy expenditure and protein, respectively, in 450 post-menopausal women.

The psychosocial and diet behavior factors were body image perception, rating on the Social Desirability Scale, cognitive restraint for eating, uncontrolled eating, and emotional eating, and number of meals eaten at home.

Following were the findings-

? Participants with high social desirability scores were more likely to under-report on the FFQ for energy and protein intake compared to those with low social desirability scores.

? Participants who ate most of their meals at home were less likely to under-report on the FFQ for energy and protein compared to those who consumed a low percentage of meals at home.

? In the assessments combining FFQ, 4DFR, 24HR with age, BMI, race, and the psychosocial and diet behavior variables, the six psychosocial and diet variables explained 1.98%, 2.24%, and 2.15% of biomarker variation for energy, protein, and protein density respectively.

The researchers thus concluded that adding psychosocial and diet behavior factors to the assessment methods can strengthen the precision of the assessments by correcting self-report for measurement error.

The study has been published in the Nutrition Journal.

Source-Medindia

View the original article here

DM

Friday, June 21, 2013

Dietary supplement of bovine meat, oysters from brain disorders of fighting

Sunday, June 16, 2013

Self-Reported Dietary Fibs Distort Survey Results