Remission Rates are Lower in Obese and Overweight RA Patients

by Kathy Jones on? June 15, 2013 at 2:34 PM Lifestyle News A new study presented at the Annual Congress of the European League Against Rheumatism, EULAR 2013, reveals that obese and overweight rheumatoid arthritis patients displayed lower remission rates and required twice as much drug therapy compared to normal weight patients.
Researchers led by Elisa Gremese, from Catholic University of the Sacred Heart, Rome, followed 346 women who had Early Rheumatoid Arthritis (ERA) and who adhered to strict follow-up visits. More than three quarters of the patients were women with 168 patients being normal weight, 135 overweight and 43 obese.

All of the patients received a weekly dose of up to 25mg of methotrexate, with or without steroids, followed by a combination with a tumor necrosis factor (TNF) blocker if a response of good or better. The researchers also recorded the body mass index (BMI) of the patients along with ACR/EULAR core data while clinical remission was evaluated on each visit.

The researchers found that lower remission rates were sustained for a longer period among overweight and obese patients with more number of patients also undergoing anti-TNF therapy for 12 months of follow-up compared to normal weight patients. "Data suggest that in ERA patients, not only obesity but also overweight, associates with a lower percentage of success in obtaining remission", the researchers wrote in their report.

Source-Medindia

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Comforts of Modern Life Lower Tolerance Level

Earlier days, people's energies were focused on basic needs like having food to eat and a roof over one's head. Now, there seems to be no concern for all these basic necessities as they are met easily. Our level of comfort has gone up to such an extent that we are pampered to a point where the slightest discomfort can cause to break into a sweat and behave like kids.

Road rage, violence and display of anger for frivolous reasons are common sight these days. A good way to keep a check on anger is to constantly question ourselves if things that make us angry are really a survival issue? If it is not life and death, then it does not warrant anger.

Researchers said that anger is 'hard wired ' into our brain and sometimes when we get angry without any purpose it can go wrong and get us into a rage.

It will pay to stop short, adopt the 'counting till 10 technique' or walk away from the situation to exercise restraint when angry and calm down.

Source-Medindia

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