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Showing posts with label supplement. Show all posts
Showing posts with label supplement. Show all posts

Friday, July 19, 2013

Herbal Supplement Use Popular in Cosmetic Surgery Patients


"It is extremely important to investigate the use of herbal medicines, as many of these supplements can put the surgical patient at risk," writes ASPS Member Surgeon Dr. Bahman Guyuron and colleagues of Case Western Reserve University, Cleveland. They advise patients to stop taking supplements at least two weeks before cosmetic plastic surgery.

Many Cosmetic Surgery Patients Use Herbal Supplements The researchers analyzed 200 patients undergoing cosmetic facial surgery (such as facelift surgery or rhinoplasty). The patients' preoperative medication lists were reviewed to determine how many patients were taking herbal supplements and what types they were using. More than 80 percent of patients were women; the average age was 45 years.

Forty-nine percent of patients were using at least one type of supplement. Vitamin and mineral supplements only?most commonly multivitamins, vitamin D, calcium and vitamin B?were used by 25% of patients. Twenty-two percent were taking animal- and plant-based supplements?most commonly fish oil?in addition to vitamins and minerals.

Only 2.5 percent of patients were taking animal and plant-based supplements only. Older patients and women were more likely to report supplement use.

Overall, patients reported taking 53 different types of supplements. The average number of supplements was 2.8 per patient, although one patient was taking 28 different supplements.

Many Linked to Bleeding or Other Risks Thirty-five patients were taking supplements that have been linked to an increased risk of bleeding, such as bilberry, bromelain, fish oil, flaxseed oil, garlic, methylsulfonylmethane (MSM), selenium and vitamin E. In Dr. Guyuron's practice, patients were advised to stop taking supplements two to three weeks before surgery. The researchers write, "Therefore, 17.5 percent of all patients?would have been at risk of bleeding" if they had not discontinued supplement use.

Dietary supplements are widely used in the United States. Since supplements are not regulated, there is a "severe lack" of data on their safety and effectiveness, according to Dr. Guyuron and colleagues. Because patients regard supplements as safe, "natural" products, they may not tell doctors about supplements when asked what medications they are taking.

However, many of these products have side effects that could lead to problems in surgical patients. In addition to the supplements potentially related to bleeding risk mentioned above, other popular supplements with potential adverse effects include echinacea, ephedra (ma huang), ginkgo, ginseng, kava, St John's wort, valerian, feverfew and ginger.

"These high risk supplements...are quite commonly used and the surgeon must elicit a complete history in order to avoid the known adverse consequences of supplement use on surgical outcome," Dr. Guyuron and coauthors write. They emphasize their policy of advising patients to stop taking supplements is consistent with current recommendations for preoperative patient evaluation.

Source-Eurekalert


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Friday, June 21, 2013

Dietary supplement of bovine meat, oysters from brain disorders of fighting

by Sheela Philomena on May 25, 2013 at 12:23 News Diet & Nutrition phosphatidylserine - food supplement produced from beef, soya and oyster has been found to improve cognition and slow memory. Help of phosphatidylserine degenerative brain disorders combat, including Parkinson's disease and the Familial Dysautonomia (FD). Food Supplement from Beef, Oysters Fights Brain Disorders
It's the determination made by a team led by Professor Gil Ast and Dr. Ron Bochner of the Tel Aviv University Department of Human Molecular Genetics.

FD, a rare genetic disease that impact on the nervous system and seems almost exclusively among the Ashkenazi Jewish population, a genetic mutation prevents the brain from the manufacture of IKAP protein in good health - probably with a hand in cell migration and help connections between nerves - leading to early degeneration of neurons.

When the supplement was applied to cells taken from patients of the FD, the improved gene function and elevation of the IKAP protein level was observed, reports Prof. Ast.

These results have been replicated in a second experiment, to administer the supplement orally to populations of mice with FD.

The results are very encouraging, said Prof. Ast.

"We see such an effect on the brain - the most important body in relation to this disease - shows that the supplement can cross the blood - brain barrier even when administered by the oral route and accumulate in sufficient quantities in the brain," he said.

Already approved for use in addition to the FDA, phosphatidylserine contains an essential molecule for the transmission of signals between nerve cells in the brain. Prof. Ast and fellow researchers decided to check if the same chemical that is naturally synthesized in the body and known to increase the memory capacity, that could affect the genetic mutation that leads to FD.

Researchers have applied a supplement derived from oysters, supplied by the Israeli firm Enzymotec, FD patients cells. Noticing a strong effect on the gene, including a jump in the production of IKAP protein in good health, they then tested the same supplement on murine models of FD, designed with the same genetic mutation that causes the disease in humans.

The mice received the supplement orally, every two days for a period of three months. Then, researchers conducted genetic tests comprehensive to evaluate the results of the treatment.

"We found a significant increase of protein in all tissues of the body," revealed Prof. Ast, including an increase in liver and increased in the brain.

"While the dietary supplement manufactures not new nerve cells, it delays probably the death of those that already exist," he added.

The supplement is able to improve the conditions in the brain, even when administered orally, is an important finding, distinguished professor of Ast.

In addition, according to the researchers, that the positive effects of the supplement to extend beyond the production of IKAP. Not only impacted phosphatidylserine gene associated with FD, but it has also changed the level of a total of 2400 other genes - hundreds of which have been connected to Parkinson's disease in previous studies.

Researchers believe that the supplement can have a beneficial effect on a number of degenerative diseases of the brain, concluded Professor Ast, including significant potential for the development of new drugs that would help the tens of millions of people around the world suffering from these devastating diseases.

The results were published in the journal Human Molecular Genetics.

Source-ANI

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